The worst part is not in making a mistake but in trying to justify it, instead of using it as a heaven-sent warning of our mindlessness or our ignorance.

I would be the last to deny that the greatest scientific pioneers belonged to an aristocracy of the spirit and were exceptionally intelligent, something that we as modest investigators will never attain, no matter how much we exert ourselves. Nevertheless ... I continue to believe that there is always room for anyone with average intelligence ... to utilize his energy and ... any man could, if he were so inclined, be the sculptor of his own brain, and that even the least gifted may, like the poorest land that has been well-cultivated and fertilized, produce an abundant harvest.

Buffon said unreservedly, "Genius is simply patience carried to the extreme." To those who asked how he achieved fame he replied: "By spending forty years of my life bent over my writing desk."

In my own view, some advice about what should be known, about what technical education should be acquired, about the intense motivation needed to succeed, and about the carelessness and inclination toward bias that must be avoided is far more useful than all the rules and warnings of theoretical logic.

Physical pain is easily forgotten, but a moral chagrin lasts indefinitely.

If a photographic plate under the center of a lens focused on the heavens is exposed for hours, it comes to reveal stars so far away that even the most powerful telescopes fail to reveal them to the naked eye. In a similar way, time and concentration allow the intellect to perceive a ray of light in the darkness of the most complex problem.

Every man if he so desires becomes sculptor of his own brain.