You can't underestimate anyone.

It's remarkable she [Venus Williams] plays at all, given her Sjögren's syndrome [an autoimmune disorder that can cause joint pain]. She's back, winning tournaments. She didn't allow society to tell her, "You have this disease; you can't do that anymore." I look at her, like, "She's not playing at 100 percent. You are. You don't have excuses." Knowing what she went through helped me try to be a more positive person.

I just never give up. I fight to the end. You can't go out and say, 'I want a bag of never-say-die spirit.' It's not for sale. It has to be innate.

Everybody who plays me plays me so hard because they always want to beat me.

I've always considered myself the best and the top. I never considered that I was out of it.

I'm proud to have opened [two] schools in Africa and one in Jamaica [through the Serena Williams Fund and its partners]. I was given a lot. I was given two parents. That's already starting above a lot of kids. And then I was given the opportunity to play tennis and parents who supported that. I feel I can give back.

Those who say that Serena isn't serious about tennis; she wants to go Hollywood. That's true, about Hollywood. I would love to get a lot of acting gigs. But you wouldn't believe the stuff I've turned down because of my tournament schedule...I would do well beside (comedian) Chris Tucker.