I remember saying, very almost jokingly, I'm going to take over the world through television, that's my plan. And I said it to my agent, and I said it to my friends, and I said it to myself.

I want my daughters to see me and know me as a woman who works. I want that example set for them... I am a better mother for it. The woman I am because I get to run Shondaland, because I get write all day, because I get to spend my days making things up, that woman is a better person - and a better mother. Because that woman is happy. That woman is fulfilled. That woman is whole. I wouldn't want them to know the me who didn't get to do this all day long. I wouldn't want them to know the me who wasn't doing.

Dreams are lovely. But they are just dreams. Fleeting, ephemeral, pretty. But dreams do not come true just because you dream them. It's hard work that makes things happen. It's hard work that creates change.

The only limit to success is your own imagination.

I never, ever pay attention to the ratings. I stopped paying attention to the ratings somewhere around season two or three of Grey's. It's something I have no control over, so I don't even pay attention.

There is no longer one way to consume TV. Some shows you want to watch live, some shows you only discover through streaming, some shows you just feel you need to DVR.

I really don't think there's a world in which you can do anything with anybody. Because we're in the world of the White House, I think there are certain things you can do, and larger things that can happen, but I don't think you can do anything.