If there's a seminal discovery in oncology in the last 20 years, it's that idea that cancer genes are often mutated versions of normal genes.
Siddhartha MukherjeeI left Delhi in 1989 and remember very little of how life used to be then. Increasingly, in my recent visits to Delhi, I've started to realize that the city has become intellectually very lively. It makes me want to discover the city over and over again.
Siddhartha MukherjeeI believe the biggest breakthroughs on cancer could come from brilliant researchers based in India.
Siddhartha MukherjeeSandeep Jauharโs Doctored is a passionate and necessary book that asks difficult questions about the future of medicine. The narrative is gripping, and the writing is marvelous. But it was the gravity of the problemโso movingly toldโthat grabbed and kept my attention throughout this remarkable work.
Siddhartha MukherjeeIn the laboratory, we call this the six-degrees-of-separation-from-cancer rule: you can ask any biological question, no matter how seemingly distant-what makes the heart fail, or why worms age, or even how birds learn songs-and you will end up, in fewer than six genetic steps, connecting with a proto-oncogene or tumor suppressor.
Siddhartha MukherjeeI wanted to explore cancer not just biologically, but metaphorically. The idea that tuberculosis in the 19th century possessed the same kind of frightening and decaying quality was very interesting to me, and it seemed that one could explore the idea that every age defined its own illness.
Siddhartha Mukherjee