I'd probably want to teach at university, because children would drive me insane. I suspect it would be English literature, Shakespeare and so forth. I've always been deeply, deeply in love with that kind of thing.

there is no reason why anyone should understand how it works… and of course no reason why anyone should care … unless you are curious, in which case I love you, for curiosity about the world and all its corners is a beautiful thing.

You don't get depressed because bad things happen to you. That's getting pissed off and annoyed. That's reasonable. Someone hits you in the face you go ow, you know that's... but depression is something that happens like weather to you inside you.

The most natural way you would attempt to cope with something inside you that is affecting your moods and your energy levels is to intervene with chemicals to help and because medical science hasn't come up with pharmaceuticals that do particularly well you tend to reach for the chemicals that are outside the Pharma counter, i.e. narcotics and alcohol because they can guarantee your mood more or less.

A cousin of mine who was a casualty surgeon in Manhattan tells me that he and his colleagues had a one-word nickname for bikers: Donors. Rather chilling.

The point about manic depression or bipolar disorder, as it's now more commonly called, is that it's about mood swings. So, you have an elevated mood. When people think of manic depression, they only hear the word depression. They think one's a depressive. The point is, one's a manic-depressive.

The stranger might laugh and seem to enjoy the writing, but you hug to yourself the thought that they didn't quite understand its force and quality the way you do - just as your friends (thank heavens) don't also fall in love with the person you are going on and on about to them.