We each exist for but a short time, and in that time explore but a small part of the whole universe

I’m the archetype of a disabled genius, or should I say a physically challenged genius, to be politically correct. At least I’m obviously physically challenged. Whether I’m a genius is more open to doubt.

You cannot predict the future.

thus, in a sense, we are all doomed. even if we stay away from black holes

I think the next [21st] century will be the century of complexity. We have already discovered the basic laws that govern matter and understand all the normal situations. We don't know how the laws fit together, and what happens under extreme conditions. But I expect we will find a complete unified theory sometime this century. The is no limit to the complexity that we can build using those basic laws.

One of the basic rules of the universe is that nothing is perfect. Perfection simply doesn't exist.....Without imperfection, neither you nor I would exist

However difficult life may seem, there is always something you can do and succeed at.