I can envision observations and experiments that would disprove any evolutionary theory I know.
Stephen Jay GouldNatural selection is just three factors - over-production, variation, and inheritance combined to produce adaptation to changing local environments. It's not a principle or progress; it's just a principle of local adaptation. You don't make better creatures in any cosmic sense; you make creatures that are better suited to the changing climates of their local habitats.
Stephen Jay GouldMy own field of paleontology has strongly challenged the Darwinian premise that life's major transformations can be explained by adding up, through the immensity of geological time, the successive tiny changes produced generation after generation by natural selection.
Stephen Jay Gould