The absence of fossil evidence for intermediary stages between major transitions in organic design, indeed our inability, even in our imagination, to construct functional intermediates in many cases, has been a persistent and nagging problem for gradualist accounts of evolution.

Some beliefs may be subject to such instant, brutal and unambiguous rejection. For example: no left-coiling periwinkle has ever been found among millions of snails examined. If I happen to find one during my walk on Nobska beach tomorrow morning, a century of well nurtured negative evidence will collapse in an instant.

Humans are not the end result of predictable evolutionary progress, but rather a fortuitous cosmic afterthought, a tiny little twig on the enormously arborescent bush of life, which if replanted from seed, would almost surely not grow this twig again.

The world is too complex for subsumption under any general theory of change.

The world is full of signals that we don't perceive.

People are clever, but almost no one ever devises an optimal quip precisely at the needed moment. Therefore, virtually all great one-liners are later inventions - words that people wished they had spouted, but failed to manufacture at the truly opportune instant.

... many folks take them seriously because they just 'know' that evolution can never be seen in the immediate here and now. In fact, a precisely opposite situation prevails: biologists have documented a veritable glut of cases for rapid and eminently measurable evolution on timescales of years and decades.