Our children are exposed to 10, 20, 30 times the number of words that our great-grandfathers were exposed to. We're exposed in a single day or two to more horror on our Internet Web pages than our great-grandfathers were exposed to in decades of living. We have not created modern minds for that modern world. Science and technology has just dumped it on us. And I think people yearn for it. I think you see it in what's popular. Why are people wanting to learn about meditation and talking about a purpose-driven life? It's because they know more is needed in the modern world.

Almost all people suffer some form of intense inner pain at some times in their lives. The suffering might be depression, anxiety, substance abuse, or suicidal thoughts and it results from the battles we wage against our thoughts as we futilely try to get rid of our historie.

I kind of look at what's on the T-shirts and I see another solution, which also worries me. I see "Just do it." "No fear." - this kind of suppressive response to the treacle that the culture tries to define for us as a meaningful life also blows up on you. "No fear" is not something that you should put on your shirt. How about "I can hold my fear and still connect with you"? Put that on your shirt. "It's okay to be me, with all of my history." Put that on your shirt.

The changes that we can make in the culture can be there for people that we will never meet, that will never know us, and that's what keeps me up at night. It's what excites me about science, that we can learn ways of being with each other. And the behavioral sciences have not been enough of a part of cultural development. The physical sciences have; the behavioral sciences have not. And I would like to see if we can bring some things into human culture that would humanize and soften and empower people.

There is a middle path between indulgence and suppression, but the culture has overwhelmed that in the cacophony that has been created in the modern world and the commercial encouragement of avoidance and indulgence on the one hand, or suppression and "just do it," treating yourself as an object on the other. We've got to find a way that's more compassionate, softer, that allows us to move forward towards the kind of lives that we really want to live.

I want good science, and I want it to be realistically marketed. I wouldn't like only two countries on the planet that allow pharmaceutical companies to market directly to people, New Zealand and the United States. It ought to be better regulated. And when it's presented to people, it ought to be presented in a way that's realistic. For example, often people will prescribe antidepressant medications, and we'll say, you have a brain disease; you'll have to be on these medications permanently. There is no biological marker for depression. It's not true that we know that it's a brain disease.

The mental cognitive processes that we're targeting are ones that narrow human beings' repertoire and make it harder for them to learn to be more flexible, to take advantage of the opportunities in front of them. We can have something to help with in areas like child development or organizations and schools, or maybe even how peoples interact with each other, one to the other. We've taken the work into things like prejudice and stigma, because if we can't solve that we have planes flying into buildings. So it applies broadly because anywhere that a human mind goes these processes go.