The definition of happiness being very emotion-oriented - the problem is that there's too many quick and dirty ways to chase that in ways that end up being unhelpful to people. If you just have another martini or even more severe substances. But commercial culture and our media is constantly encouraging us to think that if we feel good we live well. We're only too happy to sell you goods and services from the dancing oivoids and the pill you can take, or the trips or the cars or the clothes or the women that you can get with - whatever that is that will give you the quick route to that.

What keeps me up at night in a negative way is, if we don't solve the problems of the human heart and of the human head, of human psychology, there is no technological solution so great that it can prevent the world that is coming, and a world of suitcase bombs or of the ability to pollute the planet in a way that it cannot recover, of global warming and the rest. We've created through science and technology a different world that has frightening sides to it, and psychology and behavioral science has to be part of this. We're going to have to find a way to humanize the culture itself.

Antidepressant medications, you still have some depressive thoughts. Antipsychotic medications, you still have some psychotic symptoms for the vast majority of the people taking them. But it gives them a little separation, and it doesn't control his behavior as much when you have a sad feeling, difficult thought, an odd perceptual experience. We can teach people those exact skills in therapy, you get longer-term benefits and without the side effects. So don't be sold just because a commercial interest wants to sell you things.

The government ought to help out, because the average citizen can't go out and be doing reviews of the scientific literature. And focus on the processes that have low side effects and good long-term outcomes. Right now you're going to find those in the psychosocial area, in the therapy area, in the empirically supported treatments such as ACT or cognitive behavior therapy, behavior therapy. And go there first rather than going to the pill bottle as if it's going to be the end of your journey. Very often it's only going to help, and even only to a minor degree, and more is going to be needed.

The changes that we can make in the culture can be there for people that we will never meet, that will never know us, and that's what keeps me up at night. It's what excites me about science, that we can learn ways of being with each other. And the behavioral sciences have not been enough of a part of cultural development. The physical sciences have; the behavioral sciences have not. And I would like to see if we can bring some things into human culture that would humanize and soften and empower people.

Let's take something like antidepressant medications. There's decent science saying it has an effect, but it's shockingly small after you control for penetration of the blind, people knowing that they're getting the active pills versus sugar pills, if you use an active control. It's probably only a few points. But it's a multi, multibillion-dollar industry. And by the way, has huge side effects. 40 percent of the people taking them have significant sexual side effects. And that's just one. A single antidepressant medication can be worth a billion dollars to a company.

Almost all people suffer some form of intense inner pain at some times in their lives. The suffering might be depression, anxiety, substance abuse, or suicidal thoughts and it results from the battles we wage against our thoughts as we futilely try to get rid of our historie.