Do what's good for humans, modeled on how humans already do things; ignore what's convenient for computers.

The urgent finds you; you have to find the important. Importance is not fast. It is slow. It is not superficial. It is deep. And as a result, it's extremely powerful. When important matters go wrong, they undermine everything. When they go right, they sustain everything.

A library doesn't need windows. A library is a window.

The technology of synthetic biology is currently accelerating at four times the rate of Moore's Law. It's been doing that since 2005, and it's likely to continue.

When a generation talks just to itself, it becomes more filled with folly than it might have otherwise.

[Wind energy] takes a very large footprint on the land, five to 10 times what you'd use for nuclear, and typically to get one gigawatt of electricity is on the order of 250 square miles of wind farm.

On the one hand information wants to be expensive, because it's so valuable. The right information in the right place just changes your life. On the other hand, information wants to be free, because the cost of getting it out is getting lower and lower all the time. So you have these two fighting against each other.