It is a different world than when I was growing up, and you started to just kind of maintain at thirty-five and just hope you can hope it together. People are a lot more vital than I am and doing all kinds of things and leading really important movements.

Suffering should not define you as a woman! And just because you’re a man it doesn’t mean that it doesn’t affect you! HELP HER to remove the taboos and the loneliness surrounding this disease; be understanding, show empathy, and don’t accuse her of being sensitive, delicate, or overly dramatic – this is a big opportunity for you guys to show that you care and to be a real man!

Sometimes what happens is that, when you micromanage actors and moments, it just doesn't quite live.

If you walk down the street and see someone in a box, you have a choice. That person is either the other and you're fearful of them, or that person is an extension of your family.

You just can never count on a formula, on a movie that you think is going to be a big hit, and that's why you do it. You have to choose each one for what you think you'll learn and the fun you'll have. And maybe the cool people that you work with or a character that you're going to be able to explore ... You just keep your fingers crossed.

There wasn't space to mood-up. I think Rose Byrne was just extraordinary. Talk about a character that could be really unsympathetic at times. She just jumped in these scenes that go from anger to hysteria to crying to laughing and back to anger. I just marveled.

By the time I went to the Catholic University of America, which was the time the priests were all leaving with the nuns, the more I studied about the Bible and how it came about, the more I lost my faith.