Everything's serendipitous and there's no way of knowing who's going to get sick or who's going to get hit by a bus or who's going to fall in love and who's going to get pregnant. All the things that happen, it's up for grabs so it's kind of an exercise in surrender in a way.

It didn't seem to have relevance, except in Central America or South America, countries where the church was connected to the fight of the people for economic justice. That's why it was so interesting to find myself back with Sister Helen [in Dead Man Walking], this new breed of nuns who were making a difference in the community.

What is fabulous about gay marriage is that it redefines the gender designated jobs, then you throw in transgender and you don't just have the five primary colors of the crayons. We have to really look at what it means to be a man or a woman in a much more generous and creative way.

I was very withdrawn and definitely played with dolls well into eighth grade. But I was the oldest of nine, and that grounded me in a way that I don't think I would have been grounded otherwise. So I was able to - or forced to - function practically. But I think, by nature, I was someone who lived in my head, in my imagination.

It's ridiculous that we continue to incarcerate anyone for using a substance that actually causes far less damage than alcohol. No one goes out looking for fights on marijuana. No one dies from marijuana intoxication. And no one should be jailed for possessing marijuana.

I always think that the difference between film and theater is like the difference between masturbation and making love. Because, in film, you just have to get one moment right; you're practically by yourself. And in theater, you actually have to have a relationship with the audience.

Now, as I move through my fifties, I can be professional and domestic, creative and intellectual, patient and urgent. I have learned that we should never settle for someone else's definition of who we can be. Growing to this age, I realize, is kind of like feeling your voice deepen. It's still your voice, but it has more substance, and it sounds like it knows its own origins.