We were friends with Jonathan Demme. We were all down on the West Side of New York, and I think I met Kurt Vonnegut through Edith Demme. And then I was lucky to do Who Am I This Time? 1982, which was an adaptation of his short story that Jonathan Demme directed with Chris Walken and I, and that really cemented the friendship.

My aunt had given me these rosary beads that were glow-in-the-dark. So all of a sudden I look down and they're glowing, and I'm looking toward the door and thinking, "Oh, my God, I don't want anything to come though here. I'm not worthy, I'm not ready." I didn't want to be one of those kids who sees Our Lady of Fatima.

I look forward to being older, when what you look like becomes less and less an issue and what you are is the point.

At the end of your life, you are going to want to know that you made some kind of difference.

Now, as I move through my fifties, I can be professional and domestic, creative and intellectual, patient and urgent. I have learned that we should never settle for someone else's definition of who we can be. Growing to this age, I realize, is kind of like feeling your voice deepen. It's still your voice, but it has more substance, and it sounds like it knows its own origins.

I always think that the difference between film and theater is like the difference between masturbation and making love. Because, in film, you just have to get one moment right; you're practically by yourself. And in theater, you actually have to have a relationship with the audience.

When my children wake up in the morning they know they will eat breakfast, get hugs from their parents, go to a good, safe school. Plates are full and store windows are glittering. But at the same time the great majority of the world's children and women stand - no - shiver on the precipice