When you get new people in, you're going to have a breath of fresh air and there's going to be a window when people will decide what direction to go. It'll be determined by outside events, by the personalities that occupy those positions, and by the treatment they receive both from the press and the public, of the honeymoon period.

The real secrets start leaking out when there are too many secrets because people can't remember what's a real secret. There's a very famous line by National Security Advisor McGeorge Bundy: "If you guard your toothbrushes and your diamonds with equal zeal, you'll lose fewer toothbrushes and more diamonds." And that's where we are right now.

It will be important to restore those provisions, those disclose provisions, those release provisions so that presidents are indeed held accountable and their information and papers are made public.

An attitudinal sea change. I think that's the hardest one to fix. Presidential directives, bills, provisions can all be rescinded, repealed, amended, but attitudes linger. The hardest thing is going to be to try to reverse an attitude, a bunker mentality that equates secrecy with either security or heightened efficiency and that regards transparency as an invitation to mischief and trespass. This default position of operating in the shadows is going to be somewhat appealing to whomever inherits office.

Every effort is made to control information. Secrecy is just one of the toggles on their control board. The mindset is in place, and they've done a lot of hiring over eight years, not just political appointees. And they've done a lot of firing or driving people out who might have countermanded or resisted. So, institutionally, it's not going to be simply a matter of flipping the switch to undo it. You're going have to bring in people dedicated to transparency, and you have to demonstrate that there are rewards for candor.

There are benefits in the sense that there's still a certain level of confidence. But there are liabilities because you can coordinate and manipulate better as the instruments of oversight are more under your control. You don't have so many rogue operations.

A one year study by the Washington Post has documented 620 cases in which experimental drugs have been implicated in the deaths of cancer patients....And they amount to merely a fraction of the thousands of people who in recent years have died or suffered terribly from cancer experiments.