The notion of illegal plants and animals is obnoxious and ridiculous.

Nobody is smarter than you are. And what if they are? What good is their understanding doing you?

Experientially there is only one religion, and it is shamanism and shamanic ecstasy.

One way of assessing the toxicity of a drug is how do you feel the next day?

Death is the black hole of biology. It's an event horizon, and once you go over that event horizon, no information can be passed back out of the hole.

Ecstasy is a complex emotion containing elements of joy, fear, terror, triumph, surrender, and empathy. What has replaced our prehistoric understanding of this complex of ecstasy now is the word comfort, a tremendously bloodless notion. Drugs are not comfortable, and anyone who thinks they are comfortable or even escapist should not toy with drugs unless they’re willing to get their noses rubbed in their own stuff.

We are reaping the fruits of ten thousand, fifty thousand years of sowing of the fields of mind. And it is being dropped into our laps for us to create human-machine interfacing, control of genetic material, redefinition of social reality, re engineering of languages, revisioning of the planetary ecology, all these things fall upon us.