It doesn't matter what your cultural conditioning is, it falls into question under the influence of the psychedelic. And for most people that's frightening.
Terence McKennaDon't worry. You don't know enough to worry. . . . Who do you think you are that you should worry, for cryin' out loud. It's a total waste of time. It presupposes such a knowledge of the situation that it is, in fact, a form of hubris.
Terence McKennaCultivate an ongoing stream of self-description, telling yourself what is happening. Get used to the idea that mind can penetrate the immediate surface of being and reveal the tactile density of it as a manifold whose measure cannot be immediately taken by the eyes, that it's deep, it's connected, it's complex. Everything holds within itself the anticipation and the memory of everything else.
Terence McKenna