An accident, a random change, in any delicate mechanism can hardly be expected to improve it. Poking a stick into the machinery of one's watch or one's radio set will seldom make it work better.
Theodosius DobzhanskyThe foundations of population genetics were laid chiefly by mathematical deduction from basic premises contained in the works of Mendel and Morgan and their followers. Haldane, Wright, and Fisher are the pioneers of population genetics whose main research equipment was paper and ink rather than microscopes, experimental fields, Drosophila bottles, or mouse cages. Theirs is theoretical biology at its best, and it has provided a guiding light for rigorous quantitative experimentation and observation.
Theodosius DobzhanskyThe business of proving evolution has reached a stage when it is futile for biologists to work merely to discover more and more evidence of evolution. Those who choose to believe that God created every biological species separately in the state we observe them, but made them in a way calculated to lead us to the conclusion that they are the products of an evolutionary development are obviously not open to argument. All that can be said is that their belief is an implicit blasphemy, for it imputes to God an appalling deviousness.
Theodosius DobzhanskyEvolutionary plasticity can be purchased only at the ruthlessly dear price of continuously sacrificing some individuals to death from unfavourable mutations. Bemoaning this imperfection of nature has, however, no place in a scientific treatment of this subject.
Theodosius Dobzhansky