Man can sin against nature in two ways. First, when he sins against his specific rational nature, acting contrary to reason. In this sense, we can say that every sin is a sin against man's nature, because it is against man's right reason.

Reasoning is compared to understanding as movement is to rest, or acquisition to possession.... Since movement always proceeds from something immovable, and ends in something at rest, hence it is that human reasoning, in the order of inquiry and discovery, proceeds from certain things absolutely understood--namely, the first principles; and, again, in the order of judgment, returns by analysis to first principles, in the light of which it examines what it has found. Now it is clear that rest and movement are not to be referred to different powers, but to one and the same.

Given the sin of impiety through which they [the Romans] sinned against the divine nature [by idolatry], the punishment that led them to sin against their own nature followed.... I say, therefore, that since they changed into lies [by idolatry] the truth about God, He brought them to ignominious passions, that is, to sins against nature; not that God led them to evil, but only that he abandoned them to evil.

Whatever is received is received according to the nature of the recipient.

We should love others truly, for their own sakes rather than our own.

There is but one Church in which men find salvation, just as outside the ark of Noah it was not possible for anyone to be saved.

Behold our refutation of the error. It is not based on documents of faith, but on the reasons and statements of the philosophers themselves. If then anyone there be who, boastfully taking pride in his supposed wisdom, wishes to challenge what we have written, let him not do it in some corner nor before children who are powerless to decide on such difficult matters. Let him reply openly if he dare. He shall find me there confronting him, and not only my negligible self, but many another whose study is truth.