Difference of opinion leads to enquiry, and enquiry to truth; and I am sure...we both value too much the freedom of opinion sanctioned by our Constitution, not to cherish its exercise even where in opposition to ourselves.

It is a [disputed] question, whether the circulation of paper, rather than of specie [gold and silver coin], is a good or an evil I believe it to be one of those cases where mercantile clamor will bear down reason, until it is corrected by ruin.

It is between fifty and sixty years since I read it (i.e. the Book of Revelations), and I then considered it merely the ravings of a maniac, no more worthy nor capable of explanation than the incoherence of our own nightly dreams.

Preachers dread the advance of science as witches do the approach of daylight.

The issue for patents for new discovers has given a spring to invention beyond my conception.

The care of every man's soul belongs to himself. But what if he neglect the care of it? Well what if he neglect the care of his health or his estate, which would more nearly relate to the state. Will the magistrate make a law that he not be poor or sick? Laws provide against injury from others; but not from ourselves. God himself will not save men against their wills.

I see,... and with the deepest affliction, the rapid strides with which the federal branch of our government is advancing towards the usurpation of all the rights reserved to the States, and the consolidation in itself of all powers, foreign and domestic; and that, too, by constructions which, if legitimate, leave no limits to their power... It is but too evident that the three ruling branches of [the Federal government] are in combination to strip their colleagues, the State authorities, of the powers reserved by them, and to exercise themselves all functions foreign and domestic.