[T]he opinion which gives to the judges the right to decide what laws are constitutional and what not, not only for themselves, in their, own sphere of action, but for the Legislature and Executive also in their spheres, would make the Judiciary a despotic branch.

A good cause is often injured more by ill-timed efforts of its friends than by the arguments of its enemies. Persuasion, perseverance and patience are the best advocates on questions depending on the will of others.

Difference of opinion leads to enquiry, and enquiry to truth; and I am sure...we both value too much the freedom of opinion sanctioned by our Constitution, not to cherish its exercise even where in opposition to ourselves.

If once the people become inattentive to the public affairs, you and I, and Congress and Assemblies, Judges and Governors, shall all become wolves. It seems to be the law of our general nature, in spite of individual exceptions.

[All religious sects] dread the advance of science as witches do the approach of daylight; and scowl on the fatal harbinger announcing the subversion of the duperies in which they live.

Self-love . . . is the sole antagonist of virtue, leading us constantly by our propensities to self-gratification in violation of our moral duties to others.

[The Federal Convention] is really an assembly of demigods.