For the power given to Congress by the Constitution does not extend to the internal regulation of the commerce of a State (that is to say, of the commerce between citizen and citizen,) which remain exclusively with its own legislature; but to its external commerce only, that is to say, its commerce with another State, or with foreign nations, or with the Indian tribes.

Difference of opinion leads to enquiry, and enquiry to truth; and I am sure...we both value too much the freedom of opinion sanctioned by our Constitution, not to cherish its exercise even where in opposition to ourselves.

We have solved, by fair experiment, the great and interesting question whether freedom of religion is compatible with order in government and obedience to the laws. And we have experienced the quiet as well as the comfort which results from leaving every one to profess freely and openly those principles of religion which are the inductions of his own reason and the serious convictions of his own inquiries.

If I am to meet with a disappointment, the sooner I know it, the more of life I shall have to wear it off.

Private enterprise manages so much better all the concerns to which it is equal.

I believe the states can best govern our home concerns, and the general government our foreign ones.

Still we did not expect to be without rubs and difficulties; and we have had them. First the detention of Western posts: then the coalition of Pilnitz, outlawing our commerce with France, and the British enforcement of the outlawry. In your day French depredations; in mine English, and the Berlin and Milan decrees: now the English orders of council, and the piracies they authorize. When these shall be over, it will the impressment of our seamen, or something else; and so we have gone on, and so we shall go on, puzzled and prospering beyond example in the history of man.