It is prima facie highly implausible that life as we know it is the result of a sequence of physical accidents together with the mechanism of natural selection. We are supposed to abandon this naïve response, not in favor of a fully worked out physical/chemical explanation but in favor of an alternative that is really a schema for explanation, supported by some examples. What is lacking, to my knowledge, is a credible argument that the story has a nonnegligible probability of being true.
Thomas NagelOnce we have taken the backward step to an abstract view of our whole system of beliefs, evidence, and justification, and seen that it works only, despite its pretensions, by taking the world largely for granted, we are not in a position to contrast all these appearances with an alternative reality. We cannot shed our ordinary responses, and if we could it would leave us with no means of conceiving a reality of any kind.
Thomas NagelWithout consciousness the mind-body problem would be much less interesting. With consciousness it seems hopeless.
Thomas NagelEverything, living or not, is constituted from elements having a nature that is both physical and nonphysical - that is, capable of combining into mental wholes. So this reductive account can also be described as a form of panpsychism: all the elements of the physical world are also mental.
Thomas NagelIf I thought that everything I did was determined by my circumstancse and my psychological condition, I woudl feel trapped.
Thomas NagelThe point is... to live one's life in the full complexity of what one is, which is something much darker, more contradictory, more of a maelstrom of impulses and passions, of cruelty, ecstacy, and madness, than is apparent to the civilized being who glides on the surface and fits smoothly into the world.
Thomas Nagel