Ever so often in the history of human endeavour, there comes a breakthrough that takes humankind across a frontier into a new era. ... today's announcement is such a breakthrough, a breakthrough that opens the way for massive advancement in the treatment of cancer and hereditary diseases. And that is only the beginning.

I'm the f***ing Prime Minister!

I think I made the wrong career choice

You know, one of the things I've learnt since coming out of office is how much easier it is to give the advice than take the decision. I mean, you know, it's tough.

The understanding which has driven New Labour's reform is to put the individual citizen - the patient, the parent, the pupil, the law abiding citizen - at the centre of each public service, with the service reformed to meet their individual requirements

Now, again, what the center ground has got to do is to respond to people's genuine concerns and fears.

I don't concede it at all that the intelligence at the time was wrong.