An ultimate joint challenge for the biological and the computational sciences is the understanding of the mechanisms of the human brain, and its relationship with the human mind.

The real value of tests is not that they detect bugs in the code but that they detect inadequacies in the methods, concentration, and skills of those who design and produce the code.

I couldn't resist the temptation to put in a null reference, simply because it was so easy to implement. This has led to innumerable errors, vulnerabilities, and system crashes, which have probably caused a billion dollars of pain and damage in the last forty years.

Here is a language so far ahead of its time, that it was not only an improvement on its predecessors, but also on nearly all its successors.

Premature optimization is the root of all evil in programming.

I call it my billion-dollar mistake. It was the invention of the null reference in 1965.

The price of reliability is the pursuit of the utmost simplicity. It is a price which the very rich may find hard to pay.