Premature optimization is the root of all evil in programming.

An ultimate joint challenge for the biological and the computational sciences is the understanding of the mechanisms of the human brain, and its relationship with the human mind.

Here is a language so far ahead of its time, that it was not only an improvement on its predecessors, but also on nearly all its successors.

I don't know what the language of the year 2000 will look like, but I know it will be called Fortran.

The real value of tests is not that they detect bugs in the code but that they detect inadequacies in the methods, concentration, and skills of those who design and produce the code.

Programmers are always surrounded by complexity; we cannot avoid it.... If our basic tool, the language in which we design and code our programs, is also complicated, the language itself becomes part of the problem rather than part of its solution.

The price of reliability is the pursuit of the utmost simplicity. It is a price which the very rich may find hard to pay.