Premature optimization is the root of all evil in programming.

Inside every large program is a small program struggling to get out.

An ultimate joint challenge for the biological and the computational sciences is the understanding of the mechanisms of the human brain, and its relationship with the human mind.

There are two ways of constructing a software design: One way is to make it so simple that there are obviously no deficiencies, and the other way is to make it so complicated that there are no obvious deficiencies. The first method is far more difficult.

I call it my billion-dollar mistake. It was the invention of the null reference in 1965.

The price of reliability is the pursuit of the utmost simplicity. It is a price which the very rich may find hard to pay.

Premature optimization is the root of all evil in programming.