I suppose the most important thing, the heaviest single factor in one's life, is whether one's born male or female. In most societies it determines one's expectations, activities, outlook, ethics, manners - almost everything. Vocabulary. Semiotic usages. Clothing. Even food. Women... women tend to eat less... It's extremely hard to separate the innate differences from the learned ones. Even where women participate equally with men in the society, they still after all do all the childbearing, and so most of the child-rearing.
Ursula K. Le GuinAnd he began to see the truth, that Ged had neither lost nor won but, naming the shadow of his death with his own name, had made himself whole: a man who, knowing his whole true self, cannot be used or possessed by any power other than himself, and whose life therefore is lived for life's sake and never in the service of ruin, or pain, or hatred, or the dark.
Ursula K. Le GuinMy imagination makes me human and makes me a fool; it gives me all the world, and exiles me from it.
Ursula K. Le GuinThere are souls, he thought, whose umbilicus has never been cut. They never got weaned from the universe. They do not understand death as an enemy; they look forward to rotting and turning into humus.
Ursula K. Le Guin