In the fetus, or a really young child, all the different brain areas are connected to each other, diffusely. And as the brain develops, the excess connections are turned off, so you get very specialized areas. So most people have really specialized talents. What happens in creative people is this pooling doesn't take place.

Here is this three-pound mass of jelly you can hold in the palm of your hand, and it can contemplate the vastness of interstellar space. It can contemplate the meaning of infinity and it can contemplate itself contemplating on the meaning of infinity.

The brain abhors discrepancies.

You cant just take an image and randomly distort it and call it art - although many people in La Jolla where I come from do precisely that.

What do we mean by "knowledge" or "understanding"? And how do billions of neurons achieve them? These are complete mysteries. Admittedly, cognitive neuroscientists are still very vague about the exact meaning of words like "understand," "think," and indeed the word "meaning" itself.

People think of art and science as being fundamentally opposed to each other, because art is about celebrating individual human creativity, and science is about discovering general principles, not about individual people. But in fact, the two have a lot in common, and the creative spirit is similar in both.

Think about what artists, novelists and poets have in common: the ability to engage in metaphorical thinking, linking seemingly unrelated ideas, such as, 'It is the east, and Juliet is the Sun.'