There are 100 billion neurons in the adult human brain, and each neuron makes something like 1,000 to 10,000 contacts with other neurons in the brain. Based on this, people have calculated that the number of permutations and combinations of brain activity exceeds the number of elementary particles in the universe.

What do we mean by "knowledge" or "understanding"? And how do billions of neurons achieve them? These are complete mysteries. Admittedly, cognitive neuroscientists are still very vague about the exact meaning of words like "understand," "think," and indeed the word "meaning" itself.

Think about what artists, novelists and poets have in common: the ability to engage in metaphorical thinking, linking seemingly unrelated ideas, such as, 'It is the east, and Juliet is the Sun.'

In fact, on one occasion, a rather pedantic experimental psychologist was telling him about a long, complicated experiment he had done, incorporating all the proper controls and using considerable technical virtuosity. When he saw Crick's exasperated expression he said, "but Dr. Crick, we have got it right - we know it's right," Crick's response was, "The point is not whether it's right. The point is: does it even matter whether its right or wrong?"

People think of art and science as being fundamentally opposed to each other, because art is about celebrating individual human creativity, and science is about discovering general principles, not about individual people. But in fact, the two have a lot in common, and the creative spirit is similar in both.

What the artist tries to do (either consciously or unconsciously) is to not only capture the essence of something but also to amplify it in order to more powerfully activate the same neural mechanisms that would be activated by the original object.

Without ducking responsibility, what's wrong with medicine today is that it is predicated on providing treatment, not on reducing suffering. Not on solving problems.