Startups allow technologists and scientists to take risks and change plans in a way that would be frowned upon in a big company. Having said that, big companies will play a key role in certain areas and in partnerships with little companies. Each has its strengths.

Imagine the world of mobile based on Nokia and Motorola if Apple had not been restarted by a missionary entrepreneur named Steve Jobs who cared more for his vision than being tactical and financial.

Big data will replace the need for 80% of all doctors

In my view, it’s irreverence, foolish confidence and naivety combined with persistence, open mindedness and a continual ability to learn that created Facebook, Google, Yahoo, eBay, Microsoft, Apple, Juniper, AOL, Sun Microsystems and others.

The willingness to fail gives us the freedom to succeed.

The world is hung up on food-based biofuels. Not only are they the wrong thing, they're the uneconomic thing.

We don't need a fuel that's cleaner, we need a fuel that happens to be cleaner, but is half the price of oil.