Further, Dr. Gold said with a straight face, the pill at optimum dosage could have the side effect of impotence. Until that moment, although I'd had some trouble with his personality, I had not thought him totally lacking in perspicacity; now I was not all sure. Putting myself in Dr. Gold's shoes, I wondered if he seriously thought that this juiceless and ravaged semi-invalid with the shuffle and the ancient wheeze woke up each morning from his Halcion sleep eager for carnal fun.

I thought there's something to be said for honor in this world where there doesn't seem to be any honor left. I thought that maybe happiness wasn't really anything more than the knowledge of a life well spent, in spite of whatever immediate discomfort you had to undergo, and that if a life well spent meant compromises and conciliations and reconciliations, and suffering at the hands of the person you love, well then better that than live without honor.

The good writing of any age has always been the product of someone's neurosis.

we each devise our means of escape from the intolerable.

I'm simply the happiest, the placidest, when I'm writing, and so I suppose that that, for me, is the final answer. ... It's fine therapy for people who are perpetually scared of nameless threats as I am most of the time.

my brain had begun to endure its familiar siege: panic and dislocation, and a sense that my thought processes were being engulfed by a toxic and unnameable tide that obliterated any enjoyable response to the living world.

Depression is a disorder of mood, so mysteriously painful and elusive in the way it becomes known to the self -- to the mediating intellect-- as to verge close to being beyond description. It thus remains nearly incomprehensible to those who have not experienced it in its extreme mode.