I think that the best of my generation...have reversed the customary rules of the game and have grown more radical as they have gotten older - a disconcerting but healthy sign. To be sure, there are many youngish old fogies around and even the most illustrious of these, William Buckley, is blessed by a puzzling, recondite but undeniable charm, almost as if beneath that patrician exterior an egalitarian was signaling to get out.

I thought there's something to be said for honor in this world where there doesn't seem to be any honor left. I thought that maybe happiness wasn't really anything more than the knowledge of a life well spent, in spite of whatever immediate discomfort you had to undergo, and that if a life well spent meant compromises and conciliations and reconciliations, and suffering at the hands of the person you love, well then better that than live without honor.

Further, Dr. Gold said with a straight face, the pill at optimum dosage could have the side effect of impotence. Until that moment, although I'd had some trouble with his personality, I had not thought him totally lacking in perspicacity; now I was not all sure. Putting myself in Dr. Gold's shoes, I wondered if he seriously thought that this juiceless and ravaged semi-invalid with the shuffle and the ancient wheeze woke up each morning from his Halcion sleep eager for carnal fun.

my brain had begun to endure its familiar siege: panic and dislocation, and a sense that my thought processes were being engulfed by a toxic and unnameable tide that obliterated any enjoyable response to the living world.

A great book should leave you with many experiences, and slightly exhausted at the end. You live several lives while reading.

The madness of depression is, generally speaking, the antithesis of violence. It is a storm indeed, but a storm of murk. Soon evident are the slowed-down responses, near paralysis, psychic energy throttled back close to zero. Ultimately, the body is affected and feels sapped, drained.

In depression . . . faith in deliverance, in ultimate restoration, is absent. The pain is unrelenting, and what makes the condition intolerable is the foreknowledge that no remedy will come - - not in a day, an hour, a month, or a minute . . . It is hopelessness even more than pain that crushes the soul.