I always feel like a doctor who loses a patient on the operating table or something where I felt just devastated and I beat myself up until I get to try it the next night and “I'll get it better tonight.” So I'm hard on myself. I think I'm not alone in that regard with acting.

I got offered that role in Transamerica that Felicity Huffman did. That was a part that I was like, "Well, maybe I should've done that." I'm at peace with it, but that is one thing that I did turn down that went on to do great things for her. I wonder what would've happened if I would've done that.

It was terrifying when Aaron Sorkin announced that he was leaving West Wing, he and Tommy Schlamme. We felt like our parents were abandoning us. It was a tremendously sad day and I'm sure I will never understand exactly all the reasons why that happened.

I can't imagine trying to be in recovery. I mean it would be hard enough with just life going along in a nice way, but then when awful stuff happens, how you maintain the strength to get through it?

It's hard to describe to people how terrible it was when you could only watch cartoons at a certain time in your life.

Annette Bening should've won Oscar for American Beauty. I mean, I know Hilary Swank was there, she was so great too... Annette deserves one. She better win. I'm an Academy voter, and I voted for her.

The pre-shoot days are so relaxed and fun and the writers are laughing. I love the rehearsal process.