I got offered that role in Transamerica that Felicity Huffman did. That was a part that I was like, "Well, maybe I should've done that." I'm at peace with it, but that is one thing that I did turn down that went on to do great things for her. I wonder what would've happened if I would've done that.

I didn't understand the reasons why I was there in the Lost episode - the mysteries of the island. I just instead made my own little reality, made it as simple as possible. I figured I was a crazy woman, just a little screw loose. I don't know how I got on that island. No one could tell me how I got there either, so I just assumed I got there on a shipwreck, and I went a little nutty.

It's a little weird accepting your voice coming out of an animated character. You don't buy it at first because it's your voice and none of us like our voices when we hear them recorded back.

I love wasting time and learning to lip-sync to songs; it's a silly hobby of mine.

Comedy is a serious business. It's frustrating when I can't find the right thing that makes the crew laugh. If I don't make them laugh, I get very disappointed in myself. You don't really have a live audience, so you just depend on the crew to let you know if you're doing something funny.

I always feel like a doctor who loses a patient on the operating table or something where I felt just devastated and I beat myself up until I get to try it the next night and “I'll get it better tonight.” So I'm hard on myself. I think I'm not alone in that regard with acting.

I can't imagine trying to be in recovery. I mean it would be hard enough with just life going along in a nice way, but then when awful stuff happens, how you maintain the strength to get through it?