If you ask people what they've always wanted to do, most people haven't done it. That breaks my heart.

Breast cancer alone kills some 458,000 people each year, according to the World Health Organization, mainly in low- and middle-income countries. It has got to be a priority to ensure that more women can access gene testing and lifesaving preventive treatment, whatever their means and background, wherever they live.

Working with [Robert] De Niro taught me a lot about being an actor's director.

I always work with refugees and I think they are the most amazing people and it's a privilege to spend time with them, so I will always.

Artists raise their kids differently. We communicate to the point where we probably annoy our children. We have art around the house, we have books, we go to plays, we talk. Our focus is art and painting and dress-up and singing. It's what we love. So I think you can see how artists in some way raise other artists.

When I was growing up I wanted to adopt, because I was aware there were kids that didn't have parents. It's not a humanitarian thing, because I don't see it as a sacrifice. It's a gift. We're all lucky to have each other.

My kids are from different countries, but there's an understanding, you don't have to like a country just because you were born in it. You need to respect all countries. And be very open to each other's, of course.