David Fincher is a longtime friend. As a director, my wife had worked with him as a makeup artist when he would do Madonna videos years before, and his child and my oldest child were in preschool together, so we're kind of dad-friends through that, too.

I was always enjoying the moment. Acting, writing, looking for roles and getting involved with people and trying to create something that would be entertaining to people. With 'E.R.,' we were all very lucky to get this combination of people together in the right story in the right way to take it to the level it has reached.

I didn't start jogging or running until I was 37 years old. It was something that really helped me change my life.

Be what you are. Don't change yourself for anything. God made you that way for a reason.

So I was hugely thrilled that my first scene ever on camera was with Hal Holbrook.

To think one film makes a career is ridiculous. It's important to keep perspective and do things other than for money.

I just spent a lot of time on 'ER' for that eight years. I also started working when I was 16, so by the time I left 'ER,' I was 40 years old, I had this incredible experience, my wife had this great company, we had four kids, it was like, 'Let's go to New York and live for a while and make that the priority.'