I didn't start jogging or running until I was 37 years old. It was something that really helped me change my life.

I was always enjoying the moment. Acting, writing, looking for roles and getting involved with people and trying to create something that would be entertaining to people. With 'E.R.,' we were all very lucky to get this combination of people together in the right story in the right way to take it to the level it has reached.

So I was hugely thrilled that my first scene ever on camera was with Hal Holbrook.

There's really no point in having children if you're not going to be home enough to father them.

I didn't start jogging or running until I was 37 years old. It was something that really helped me change my life.

David Fincher is a longtime friend. As a director, my wife had worked with him as a makeup artist when he would do Madonna videos years before, and his child and my oldest child were in preschool together, so we're kind of dad-friends through that, too.

Flying back from New York, the flight attendant said 'God, I wished you were here yesterday, we had a stroke on the plane.' I said, 'If I have a stroke on a plane, I hope the pretend doctor isn't the one on the plane. I want a real doctor.'