It is, I admit, mere imagination; but how often is imagination the mother of truth?

It seems very strange ... that in the course of the world's history so obvious an improvement should never have been adopted. ... The next generation of Britishers would be the better for having had this extra hour of daylight in their childhood.

His ignorance was as remarkable as his knowledge. Of contemporary literature, philosophy and politics he appeared to know next to nothing... My surprise reached a climax, however, when I found incidentally that he was ignorant of the Copernican Theory and of the composition of the Solar System.

Have you tried to drive a harpoon through a body? No? Tut, tut, my dear sir, you must really pay attention to these details.

Philosophy, astronomy, and politics were marked at zero, I remember. Botany variable, geology profound as regards the mud stains from any region within fifty miles of town, chemistry eccentric, anatomy unsystematic, sensational literature and crime records unique, violin player, boxer, swordsman, lawyer, and self-poisoner by cocaine and tobacco.

So swift, silent and furtive were his movements like those of a trained bloodhound picking out a scent, that I could not but think what a terrible criminal he would have made had he turned his energy and sagacity against the law instead of exerting them in its defense. -Dr. Watson, The Sign of the Four

'Men die of the diseases which they have studied most,' remarked the surgeon, snipping off the end of a cigar with all his professional neatness and finish. 'It's as if the morbid condition was an evil creature which, when it found itself closely hunted, flew at the throat of its pursuer. If you worry the microbes too much they may worry you. I've seen cases of it, and not necessarily in microbic diseases either. There was, of course, the well-known instance of Liston and the aneurism; and a dozen others that I could mention.'