No: I am not tired. I have a curious constitution. I never remember feeling tired by work, though idleness exhausts me completely." ~ Sherlock Holmes

The stage lost a fine actor, even as science lost an acute reasoner, when [Holmes] became a specialist in crime.

You have a grand gift for silence, Watson. It makes you quite invaluable as a companion.

The grand thing is to be able to reason backwards.

Well, I'm a bacteriologist, you know. I live in a nine-hundred-diameter microscope. I can hardly claim to take serious notice of anything that I can see with my naked eye.

Accounts are not quite settled between us," said she, with a passion that equaled my own. "I can love, and I can hate. You had your choice. You chose to spurn the first; now you must test the other.

What can we know? What are we all? Poor silly half-brained things peering out at the infinite, with the aspirations of angels and the instinct of beasts.