One dumb-bell, Watson! Consider an athlete with one dumb-bell. Picture to yourself the unilateral development - the imminent danger of a spinal curvature. Shocking, Watson, shocking!

He [Professor Moriarty] is the Napoleon of crime, Watson. He is the organizer of half that is evil and of nearly all that is undetected in this great city. He is a genius, a philosopher, an abstract thinker. He has a brain of the first order.

I felt Holmes's hand steal into mine and give me a reassuring shake. - Watson

"I have seen those symptoms before," said Holmes, throwing his cigarette into the fire. "Oscillation upon the pavement always means an affaire de coeur."

…but it is better to learn wisdom late than never to learn it at all.

Only that I insist upon your dining with us. It will be ready in half an hour. I have oysters and a brace of grouse, with something a little choice in white wines. Watson, you have never yet recognized my merits as a housekeeper. ~ Sherlock Holmes

Well, I'm a bacteriologist, you know. I live in a nine-hundred-diameter microscope. I can hardly claim to take serious notice of anything that I can see with my naked eye.