I learned what a Birkin bag is from the price tag. You'll never forget what it is once you've paid for one.

Entertainment, really, is a dying industry.

Acting can be so much fun that it's easy to forget that what you're doing is a job. But if I've got my tie on, I'm going to work.

I was shooting a scene in my new film, No Strings Attached, in which I say to Natalie Portman, “If you miss me. you can’t text, you can’t email, you can’t post it on my Facebook wall. If you really miss me, you come and see me.

I wanted to be a genetic engineer. That was my goal in college. I wanted to figure out what the codon sequence was that causes replication in a cardio myopathic virus. That was my goal.

I don't understand shopping, it doesn't make any sense to me. As guys, we decide we want something and then we go out and buy it. Women go to the store having no idea what they're going to buy, or what they're even doing, it's like a whole different sport. It's like going to a football game to maybe watch a game. I don't get it.

The goal is not to get into a relationship; the goal is to be in a relationship.