Don’t let yourself be. Find something new to try, something to change. Count how often it succeeds and how often it doesn’t. Write about it. Ask a patient or a colleague what they think about it. See if you can keep the conversation going.

There are times when you have sharp elbows, and people are trying to muscle you out of certain meetings - because then people could leak to the press that you had a role in certain decisions. I, at twenty-six, was very impatient and didn't know how to keep my powder dry. I was running a team of seventy-five people when I had never been a boss. I was the worst boss ever.

Courage is strength in the face of knowledge of what is to be feared or hoped. Wisdom is prudent strength.

In every industrialized nation, the movement to reform health care has begun with stories about cruelty.

You know, 97 percent of the time, if you come into a hospital, everything goes well. But three percent of the time, we have major complications.

The big thing that's happened is, in the time since the Affordable Care Act has been going on, our medical science has been advancing. We have now genomic data. We have the power of big data about what your living patterns are, what's happening in your body. Even your smartphone can collect data about your walking or your pulse or other things that could be incredibly meaningful in being able to predict whether you have disease coming in the future and help avert those problems.

I chose surgery because I thought that perhaps this would make me more like the kind of person I wanted to be.