But I've swallowed my pride before, that's for sure. I'm practically lined with my mistakes on the inside like a bad-wallpapered bathroom.

The arc of history is longer than human vision. It bends. We abolished slavery, we granted universal suffrage. We have done hard things before. And every time it took a terrible fight between people who could not imagine changing the rules, and those who said, 'We already did. We have made the world new.' The hardest part will be to convince yourself of the possibilities, and hang on.

Science doesn't tell us what we should do. It only tells us what is.

I personally am inclined to approach [housework] the way governments treat dissent: ignore it until it revolts.

On the day I swore to uphold the Hippocratic oath, the small hairs on the back of my neck stood up as I waited for lightning to strike. Who was I, vowing calmly among all these necktied young men to steal life out of nature's jaws, every old time we got half a chance and a paycheck?... I could not accept the contract: that every child born human upon this earth comes with a guarantee of perfect health and old age clutched in its small fist.

Southern Appalachians have been ridiculed since the country began. In fiction, they're usually depicted in a cartoonish manner. The region is poor, and very suspicious of outsiders, so there's a sort of 'us versus them' situation. They're easy to poke fun at.

restraint equals indulgence