As James Surowiecki noted in a New Yorker article, given a choice between developing antibiotics that people will take every day for two weeks and antidepressants that people will take every day for ever, drug companies not surprisingly opt for the latter. Although a few antibiotics have been toughened up a bit, the pharmaceutical industry hasn't given us an entirely new antibiotic since the 1970s.

I can't imagine there has ever been a more gratifying time or place to be alive than America in the 1950s. No country had ever known such prosperity.

Every dog on the face of the earth wants me dead.

Cheapness is a great virtue.

English grammar is so complex and confusing for the one very simple reason that its rules and terminology are based on Latin - a language with which it has precious little in common. In Latin, to take one example, it is not possible to split an infinitive. So in English, the early authorities decided, it should not be possible to split an infinitive either. But there is no reason why we shouldn't, any more than we should forsake instant coffee and air travel because they weren't available to the Romans.

If you go out on the Appalachian Trail, you have to bring so much more equipment - a tent, sleeping bag - but if you go hiking in England, or Europe, generally, towns and villages are near enough together at the end of the day you can always go to a nice little inn and have a hot bath and something to drink.

I have long known that it is part of God's plan for me to spend a little time with each of the most stupid people on earth.