If this book has a lesson, it is that we are awfully lucky to be here-and by 'we' I mean every living thing. To attain any kind of life in this universe of ours appears to be quite an achievement. As humans we are doubly lucky, of course: We enjoy not only the privilege of existence but also the singular ability to appreciate it and even, in a multitude of ways, to make it better. It is a talent we have only barely begun to grasp.

The great failure in education, much of the time, is the lack of excitement and stimulus

The average Southerner has the speech patterns of someone slipping in and out of consciousness. I can change my shoes and socks faster than most people in Mississippi can speak a sentence.

But that's the glory of foreign travel, as far as I am concerned. I don't want to know what people are talking about. I can't think of anything that excites a greater sense of childlike wonder than to be in a country where you are ignorant of almost everything. Suddenly you are five years old again. You can't read anything, you have only the most rudimentary sense of how things work, you can't even reliably cross a street without endangering your life. Your whole existence becomes a series of interesting guesses.

It is unthinkable to have a British countryside that doesn't have actual functioning farmers riding tractors, cows in fields, things like that.

Life just wants to be; but it doesn't want to be much.

As James Surowiecki noted in a New Yorker article, given a choice between developing antibiotics that people will take every day for two weeks and antidepressants that people will take every day for ever, drug companies not surprisingly opt for the latter. Although a few antibiotics have been toughened up a bit, the pharmaceutical industry hasn't given us an entirely new antibiotic since the 1970s.