I have to admit that business-type thoughts do sneak into my head: I hope our customers pay us, I hope this stuff is decent, I hope we get it done on time. The little additions and subtractions that one has to do. Take sales, take costs and try to get that big positive number at the bottom.

SPAM is taking e-mail, which is a wonderful tool, and exploiting the idea that it's very inexpensive to send mail.

Thinking about impact on children meant adding to the agenda, both the R&D agenda and the delivery agenda, but it's amazing news, even in the scale of other tragedies.

The concept of this so-called "TerraPower reactor" is that you, in the same reactor, you both burn and breed. So, instead of making plutonium and then extracting it, we take uranium - the 99.3 percent that you normally don't do anything with - we convert that, and we burn it.

The scientific understanding of some of these [childhood] diseases is advancing quite rapidly. There's some things like premature birth or nutrition, first day deaths that we need a lot more insights so that we can build the tools to solve those problems.

I think it's fair to say that personal computers have become the most empowering tool we've ever created. They're tools of communication, they're tools of creativity, and they can be shaped by their user.

There are more people dying of malaria than any specific cancer.