My fascination is broadly with biology and the fact that our increased understanding of biology allows for breakthroughs in a broad set of diseases.

I don't have any TVs with their over-the-air receivers connected in my house. But when I'm in a hotel room or other places that have a TV, then I turn it on and flip the channels just like everybody else. I'm not immune to the lures of television. I just try to stay away from it because I like to read.

The world is not flat, and PCs are not, in the hierarchy of human needs, in the first five rungs.

The most meaningful way to differentiate your company from your competition, is to do an outstanding job with information.

Good programmers stay open minded to that even though there is no obvious way to improve what they've done they... they keep looking and they listen to what other people have to say.

Well, jobs are a great thing. You have to be a bit careful: If you raise the minimum wage, you’re encouraging labor substitution and you’re going to go buy machines and automate things - or cause jobs to appear outside of that jurisdiction. And so within certain limits, you know, it does cause job destruction. If you really start pushing it, then you’re just making a huge trade-off.

The early personal computers were not very powerful so the idea of feeding their program into a small amount of memory requires immense skill.