There are ecosystems like coral reefs [at risk] through ocean acidification. Those are valuable things that we should protect.

The belief that the world is getting worse, that we can't solve extreme poverty and disease, isn't just mistaken. It is harmful.

The general idea of the rich helping the poor, I think, is important. That your sense of justice says, why should rich kids - who barely get these diseases and almost never die of them - why should they get the vaccines, when poor kids, who actually do die from these diseases, don't get those things? It's an unbelievable inequity that there isn't that access.

The only thing I understand deeply, because in my teens I was thinking about it, and every year of my life, is software. So I'll never be hands-on on anything except software.

If somebody is considering being willing to go out and work in the field in global health, those are a particular class of heroes because it's hard to work in those places. Our foundation gets so many of our learnings from people who've been out there and seen, "this tool is not going to work there, there's more of a problem here than you know." You should really get involved in that.

I actually thought that it would be a little confusing during the same period of your life to be in one meeting when you're trying to make money, and then go to another meeting where you're giving it away. I mean is it gonna erode your ability, you know, to make money? Are you gonna somehow get confused about what you're trying to do?

The common thread for everything I do is this idea of a Web-services architecture. What does that mean? It means taking components of software and systems and having them be self-describing, so that you can aim them, ask them what their capabilities are, and communicate with them using a standard protocol.