Effective philanthropy requires a lot of time and creativity - the same kind of focus and skills that building a business requires.

Should there be cameras everywhere in outdoor streets? My personal view is having cameras in inner cities is a very good thing. In the case of London, petty crime has gone down. They catch terrorists because of it. And if something really bad happens, most of the time you can figure out who did it.

As I look forward, I'm very optimistic about the things I see ahead.

This [philanthropy] work is even more fascinating. It requires us to think harder about how we build partnerships, who we get behind. And yet we get to see progress that in some ways is even more profound than the great advances that digital technology has provided.

Having kids has been a fantastic thing for me. It's meant that I'm a little more balanced. In my twenties I worked massively, hardly took vacation at all. Now, I, with the help of my wife, I'm always making sure I've got a good balance of how I spend my time.

It is hard to smash a computer when you're laughing.

Government investment unlocks a huge amount of private sector activity, but the basic research that we put into IT work that led to the Internet and lots of great companies and jobs, the basic work we put into the health care sector, where it's over $30 billion a year in R&D that led the biotech and pharma jobs. And it creates jobs and it creates new technologies that will be productized. But the government has to prime the pump here. The basic ideas, as in those other industries, start with government investment.