I was announcing to the public, in 2006, that I'd be leaving Microsoft in a couple of years and focusing full-time on the foundation. That was the time at which we went back to New York and Warren [Buffett] announced these gifts to a number of foundations, with a very high percentage of it going to us and basically doubling our capacity.

My grade point average went from a 2.2 to a 4.0 over the summer. I wanted to get straight A's. I decided to get straight A's. I didn't want people to think I was dumb. And when you get straight A's once, its easier.

When you have the medical advances you think will they be available to everyone. Will they not just be for the rich world or even just the rich people and the rich world? Will they be for the world at large?

The belief that the world is getting worse, that we can't solve extreme poverty and disease, isn't just mistaken. It is harmful.

When you say that after World War I there was a pandemic that killed more people than the war itself, most will say: "Wait, are you kidding? I know World War I, but there was no World War 1.5, was there?" But people were traveling around after the war, and that meant the force of infection was much higher. And the problem is that the rate of travel back then was dramatically less than what we have nowadays.

In poor countries, we still need better ways to measure the effectiveness of the many government workers providing health services. They are the crucial link bringing tools such as vaccines and education to the people who need them most. How well trained are they? Are they showing up to work?

Life's not fair, get over it!